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According to research experts found that fat stored in the human body can be influenced by genetic factors. The study, published in the journal Nature Communications, and the report also told that this effect majorly dominates in women than men.


"We know that women and men tend to store fat differently - women have the ability to more easily store fat on the hips and legs, while men tend to accumulate fat around the abdomen to a higher extent," said lead author Mathias Rask-Andersen from Uppsala University in Sweden.

"This has been attributed to the effects of sex hormones such as estrogen. But the molecular mechanisms that control this phenomenon are fairly unknown," Rask-Andersen added.

For the near study on this, the researchers measured how fat was distributed in nearly 360,000 voluntary participants. The participants were asked to give their blood samples for genotyping and for seeing the distribution of electrical resistance when an electrical current is fed through the body.

Researcher suggested that genome were tested for association with the distribution of the fat to the arms, legs, or trunk and the research team also confirmed that hundreds of genes that affect the distribution of adipose tissues to the different parts of the human body.

The researchers also saw a high degree of heterogeneity between sexes.

The research also suggested that the ability in women to store the fat around the hips and legs, provides women protein against cardiovascular disease.

"The biological systems we highlight in our study have the potential to be used as points-of-intervention for new drugs that are aimed at improving the distribution of body fat and thereby reducing the risk of disease," Mathias Rask-Andersen noted.

-Simran Bhatnagar
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