Yerba santa, a plant with a long past of medicinal use in its native California, containsan active compound that could give people with Alzheimer's disease one day.This wasthe assumption that scientists at the Salk Institute for Biological Studies in La Jolla, CAcame to after testing 400 plant excerpts with known medical properties.Using a new drug-discovery screen, they tested the compounds for their aptitude todeter the things of aging on the brain.The initial round of tests produced severalexcerpts that protected alongside a type of cell death that happens in Alzheimer's andother aging-related diseases.
Natural tribes of California have long valued Yerba santa, which is the Spanish for "holyherb," very highly as a medicine for breathing diseases, fever, infections, bruising, pain,and headaches .The researchers describe their findings in a paper that now features inthe journal Redox Biology.
"And," she adds, "because age is a main risk issue, researchers are observing at waysto counter aging's effects on the brain."It is the most common cause why peoplegrow dementia .As yet, there are no treatments that cure or stop Alzheimer's disease,though some can slow or delay the development of indications for a while.According to a 2018 Alzheimer's Disease Worldwide report, dementia upsets 50 millionpeople worldwide, two-thirds of whom have Alzheimer's disease.Sterubin also presented an aptitude to remove iron from cells. Accumulation of iron canlead to a type of nerve cell damage that escorts aging and that occurs inneurodegenerative situations. The investigators now plan to use an animal model tocontrol sterubin's drug properties and safety levels in animals.
From there, they could test it in humans. To do that with a normal extract, however, itwould have to come from plants that grow under controlled conditions and then undergocleansing. Maher suggests that the more likely way onward would be to make syntheticversions of the compound.
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